Paul Sandoz reported a problem with method inlining through method handles: 
http://mail.openjdk.java.net/pipermail/hotspot-compiler-dev/2014-October/015993.html

_@ 48   MHInlineTest::testPackageMH (24 bytes)   inline (hot)
__@ 7   java.lang.invoke.LambdaForm$MH/314265080::invokeExact_MT (17 bytes)   force inline by annotation
___@ 2   java.lang.invoke.Invokers::checkExactType (30 bytes)   force inline by annotation
____@ 11   java.lang.invoke.MethodHandle::type (5 bytes)   accessor
___@ 13   java.lang.invoke.LambdaForm$DMH/285377351::invokeVirtual_LL_V (15 bytes)   force inline by annotation
____@ 1   java.lang.invoke.DirectMethodHandle::internalMemberName (8 bytes)   force inline by annotation
____@ 11   MHInlineTest$A::package_x (6 bytes)   virtual call
 
Failing test:
public class MHInlineTest {
    public static class A {
        void package_x(String s) { ... }
    }

    public static final class B extends A {
        void package_x(String s) { ... }
    }

    static final MethodHandle A_PUBLIC_X;
    static final MethodHandle A_PROTECTED_X;
    static final MethodHandle A_PACKAGE_X;
    static final MethodHandle A_PACKAGE_FINAL_X;

    static {
        try {
            A_PACKAGE_X = MethodHandles.lookup().findVirtual(
                    A.class, "package_x", MethodType.methodType(void.class, String.class));
        } catch (Exception e) {
            throw new Error(e);
        }
    }

    static final A a = new B();

    public static void main(String[] args) {
        for (int i = 0; i < 1000_0000; i++) {
            try {
                A_PROTECTED_X.invokeExact(a, x);
            } catch (Throwable throwable) {
                throw new Error(throwable);
            }
        }
    }
}